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Medicinal Leeches for Sale Natural Leech ExtractCAS No.113274-56-9 Hirudin Powder HirudiChat Now
Source Leech and its salivary glands
Composition 65-66 amino acids composed of small molecules
Category Thrombin Natural Specific Inhibitor
CAS number 113274-56-9
Molecular formula C66H93N13O25
Molecular weight 1468.53
Hirudin is one of the most active and studied components of many active ingredients extracted from Leech and its salivary glands. It is a small molecule protein consisting of 65-66 amino acids (peptides). ). Hirudin has a strong inhibitory effect on thrombin and is the strongest natural inhibitor of thrombin found so far.
1.Animal studies and clinical studies have shown that hirudin is highly effective in anticoagulant, antithrombotic, and blocking of thrombin-catalyzed activation of blood coagulation factors and platelet response and other bloody phenomena.
2.In addition, it also inhibits thrombin-induced proliferation of fibroblasts and thrombin stimulation of endothelial cells.
Compared with heparin, it not only uses less, does not cause hemorrhage, and does not depend on endogenous cofactors; heparin has the risk of causing hemorrhage and antithrombin III during the course of diffuse intravascular coagulation. It is often reduced, which will limit the efficacy of heparin, and the use of blisters will have a better effect.
1. Hirudin is a promising class of anticoagulation and anticonvulsant drugs that can be used to treat various thrombotic disorders, especially venous thrombosis and diffuse vascular coagulation;
2. It can also be used to prevent the formation of arterial thrombosis after surgery, prevent the formation of thrombus after thrombolysis or revascularization, and improve the extracorporeal blood circulation and hemodialysis.
3. In microsurgery, failure is often caused by vascular embolization at the anastomosis, and hirudin can promote wound healing. 4. Studies have also shown that hirudin can also play a role in the treatment of cancer. It can prevent the metastasis of tumor cells and has proven efficacy in tumors such as fibrosarcoma, osteosarcoma, angiosarcoma, melanoma, and leukemia.
4.Hirudin can also be combined with chemotherapy and radiation therapy to enhance efficacy due to the promotion of blood flow in tumors.
|Appearance||White or Yellowish Powder||Organoleptic Conforms|
|Mesh Size||100% through 80% mesh size||USP32<786> Conforms|
|Drying Method||spray drying||spray drying Conforms|
|Loss on Drying||≤5.0%||Eur.Ph.6.0[2.4.16] 4.39%|
|Pesticides Residue||Meet USP32<561>||USP32<561> Conforms|
|Total Plate Count||≤1000cfu/g||USP30<61> 180|
|Yeast &Mold||≤500cfu/g||USP30<61> 138|
Packaging & Shipping
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Having stock and can ship it out within 3 days when getting the payment.