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More About Cosmetic Peptide
Jun 27, 2018

I. introduction 

Cosmetic peptide  was a small molecule of degraded collagen containing amino acid groups and was generally 2-10 amino acids. Peptides are also an existing component in the human body. They are chains of amino acids. The protein we're familiar with is a polypeptide chain.

Peptides are composed of amino acids linked by peptide chains, but each peptide can be composed of a variety of different amino acids. Two amino acids are called dipeptides, three amino acids are called tripeptides, and so on. The commonly heard tripeptides, pentapeptides, and even nine-peptides are oligopeptides. Each oligopeptide chain has a different effect. Peptides usually less than 10 amino acids are called oligopeptides, those with more amino acids are called polypeptides, and more than 50 are called proteins. Due to the variety of amino acids contained, dipeptides and tripeptides also have different varieties, so there are now a variety of functions, various names of "peptides."

Peptides in the body's hormone, nerve, cell growth and reproduction in various fields, the importance is to adjust the physiological functions of each system and the cells in the body, activate the related enzymes in the body, promote metabolism between membrane permeability, or through the control of DNA transcription or affect the specific protein synthesis, eventually produce a specific physiological effect.

2. The cosmetic effect of shengpeptide in cosmetics

The biological activity of peptides depends on their amino acid composition and sequence. Almost all physiological processes in the human body are regulated by polypeptides or proteins composed of specific amino acid sequences. Bioactive peptides, therefore, become the cosmetics research and development and application of direction and new ideas, and function more and more segments, such as: anti-aging, allergy, repair, antioxidant, anti edema and promote hair regrowth, inhibit melanin, breast enhancement, weight loss, etc.

The skin is a natural barrier for the human body to resist the invasion of the external environment. It has a certain protective effect on the external stimulation, which benefits from the protective effect of the tight skin cuticle. But also the nutrition of cosmetics in the skin surface, nutrients need to infiltrate the corneous layer membrane can enter within the dermis, macromolecule and fat-soluble substances only a small amount can be through the pores, sweat pore is absorbed. So we usually used in cosmetics, mostly just stay on the surface of the skin, and bioactive peptides hairdressing, can more easily through the cuticle clearance to enter the quantity, thus play a role.

Peptide was first used by some European and American medicine makeup directly in the product, mechanism similar to the mechanism of protein and polysaccharide can promote collagen and elastic fiber, and hyaluronic acid proliferation, improve skin moisture, increase skin thickness and reduce the appearance of fine lines. Due to the different types of amino acids contained, different functions can be played to meet the needs of different functions of skin.

Iii. Peptide functional classification:

Instant wrinkles

Three kind of snake venom peptide SYN - AKE (Dipeptide Diaminobutyroyl Benzylamide Diacetate)

Snakeskin tripeptide partially blocks the nerve to transmit the muscle contraction signal, affects the cutaneous nerve conduction, relaxes the facial muscles, and reaches the effect of smoothing the dynamic lines, static lines and fine lines.

Acetyl hexapeptide-3 = ac-eemqrr-nh2, nickname Argireline)

Acetyl six peptide - 8 - also known as botox, which have influence on the excessive release nerve substances, subcutaneous transfer between nerve and muscle protein function, to slow down the face of the crow's feet, wrinkles and other dynamic grain effect best, French dermatologist study, six peptides used in eye wrinkles effect is particularly obvious.

Promote protein, polysaccharide and hyaluronic acid synthesis, improve skin quality

Three peptides GHK (Aldeline)

Tripeptides are the first known peptide arrangement and combination, and are considered as growth factors, which can stimulate the production of glucosamine polyacids and collagen. Separated from wound healing tissue in 1990, it has the effect of promoting wound healing and hyperplasia.

(peptide = GHK cooper - Cu)

Blue copper peptide is the perfect formula for divalent copper ion + trimeric peptide

Cupristatin was first used as an internal medicine to treat gastric ulcers. Copper is one of the basic elements of the body and helps heal wounds in the function of skin tissue. Copper ions can't separate into the skin, therefore, through by glycine, glycine, histidine, etc., with a copper ion link of blue copper peptides, the copper can be imported skin, perfect activating effect into full play. Cyanopepine can effectively promote the production of collagen and elastin and the anti-oxidation ability. Meanwhile, it can penetrate deeper into the skin, promote the self-repairing ability, and play an extreme role in smoothing wrinkles.

Hexapeptide 9 (Collaxyl)

Hexapeptide -9 can promote collagen production and epidermal differentiation and significantly resist wrinkles. Strong repair (especially for the repair of acne marks have a very strange effect); Fight skin flabby, make skin more elastic, firmer.

Palmitopentyl peptide-3 (palmitopentyl Pentapeptide-3 =Palmitoyl-KTTKS, nicknamed Matrixyl)

Palmitoyl five peptides - 3 is the earliest medical dermatology anti-aging ingredients such as compared with vitamin A, it can act directly on the dermis, promote collagen protein and polysaccharide hyperplasia, achieve tighten the skin, and other moisturizing ingredients, can accelerate the firming effect.

Anti - inflammatory reaction, remove red blood silk, reduce allergic discomfort

Acetylhexapeptide -49 (delisens)

Acetyl six peptide - 49 by lowering the protease activity of activated receptor 2 (PAR - 2), reduce proinflammatory response intermediate CGRP, IL6 and the release of IL8 and ease the pain of neurogenic inflammation and alleviating allergic skin, itching and other discomfort.

Acetyl tetrapeptide -40 (Telangyn)

Acetaminophen -40 reduces the spread of red lines and capillaries on the face and improves skin tone, as well as tightness and anti-photoaging effects.

Bacteriostatic, acne treatment

Palmitoyl Tripeptide-36 (Palmitoyl Tripeptide-36)

Palmitoyl tri-36 has broad spectrum antibacterial properties and can effectively inhibit pathogenic bacteria such as pseudomonas aeruginosa and acne vulgaris.

Remove eye bags and dark circles

Acetyl - 5 (Eyeseryl) and four peptides eye silk peptide Eyeliss ammonia

Acetyltetrapeptide-5, palmitotetra-7 and dipeptide VW improve the function of eye lymphatic microcirculation, skin elasticity and anti-edema, and are therefore used to relieve eye bags and dark circles.

Compact, elastic

Palmitoyl Oligopeptide

Palmitoyl oligopeptides promote the proliferation of collagen and hyaluronic acid, and improve skin moisture content and elasticity.

Acetyl dipeptide 13 (relistase)

Acetyldipeptide-13 inhibits elastase activity, enhances the skin's ability to resist stretch, and maintains elasticity and firmness.

Palmitoyl Tetrapeptide pal-gqpr (Palmitoyl Tetrapeptide 3)

Palmitoyl tetrandrine -3 ACTS like DHEA, modulates inflammatory factors, and restores skin firmness and youth.

Whiten, remove spots and brighten skin

Nine peptide 1 (Nonapeptide - 1)

When the skin by external stimuli or ultraviolet light, located in the basal layer cells of alpha melanocyte stimulating hormone will be combined with receptors on the melanocytes, direct stimulation of melanin cells, activate the tyramine acid, begin to secrete black element, nine peptide can block, suspension in the melanin formation source of alpha melanocyte stimulating hormone message transmission, avoid and melanin cell receptors, in order to reduce the melanin.

Breast enhancement

Acetylhexapeptide -38(Adifyline)

Acetylhexapeptides -38 can significantly stimulate the use of site fat synthesis, increase the volume of the chest, hips or cheeks, and shape the perfect body curve.


Peel removing tissue

Acetylhexapeptide 39 (Silusyne)

Acetyl six peptide - 39 proliferation inhibiting peroxidase body activated receptor gamma activated factor - 1 alpha (pgc-1 alpha alpha) expression, decrease the rate of adipocyte differentiation and maturation, slows down the accumulation of lipid in adipose tissue.

Light aging resistance

Three peptides - 33 (Preventhelia)

Trimeridine -33 reduces damage to cell DNA and protein directly or indirectly due to uv radiation and effectively fights against photoaging.


Acetyl hexapeptide 51 (Juveleven)

Acetylhexapeptides 51 protect DNA from damage, promote natural DNA repair and enhance cell life and vitality. Acetylhexapeptides 51 can effectively repair the properties of aging skin cells, restore skin cells youth, prevent skin damage, extend cell life, and enable you to have skin at the age of 50 and 30.

Promote the growth of hair and eyelashes

Myristopentyl pentapeptide 17

Nutmeg pentapeptidin-17 activates keratin genes that promote eyelashes, eyebrows and hair growth.

Work well under pressure

Acettetra-22 (Thermostressine)

Acetyl four peptide - 22 to increase the level of heat shock protein 70 skin, giving skin against stress stimulation and the ability to challenge every day, is particularly suited to improve the weak, tired and dark skin, restore the vitality.

Anti carbonylation and oxidation

Carnosine (carnosine)